Long-form articles exploring the science behind the data.
Neurogenesis shows up in the pop-science framing of almost every substance. Most of it is rodent work, some of it is human postmortem, and some of it is wishful extrapolation. Here's what the evidence actually supports.
Ketamine and psychedelics are often described as 'promoting neuroplasticity.' That's true but flattens a more interesting story. Chronic stress physically eliminates specific synaptic connections in the prefrontal cortex. What ketamine does, at least in mice, is regrow them in the exact positions where stress deleted them.
